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News, opinions and meeting coverage in primary care.

ESC over a perspective view of a heartbeat on a vital signs monitor.

Good Results When Giving Flu Shots to MI Survivors Still in the Hospital

Vaccination prior to discharge linked to heart benefit

ESC over a perspective view of a heartbeat on a vital signs monitor.

Lower BP Targets Again Affirmed in Major Trial

STEP trial from China shows major benefits in older population

ESC over a perspective view of a heartbeat on a vital signs monitor.

Mineral Oil Likely Accounts for Some -- But Not All -- of Vascepa's ASCVD Benefit

Danish study fans the flames of REDUCE-IT controversy

ESC over a perspective view of a heartbeat on a vital signs monitor.

Polypills Ready for Prime Time in Large Swaths of People, Researchers Say

Question now is how to implement fixed-dose combo therapy in clinical practice

A bottle of Nuplazid (pimavanserin) capsules over a photo of a senior woman hiding her eyes with her hands.

Parkinson's Drug Tied to Increased Hospitalizations, Death

Mortality risk persisted in people taking pimavanserin

Retinal imaging of nonproliferative diabetic retinopathy

Anti-VEGF Injections Preserved Vision in Severe Diabetic Retinopathy

Aflibercept also reduced vision-threatening complications

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

Driving Patterns Pinpoint Early Alzheimer's Disease

Subtle shifts in on-road behavior suggest GPS-based biomarkers may have merit

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

COVID-19: Persistent Cognitive Effects, Uptick in Alzheimer's Biomarkers

Findings link cognitive impairment and long-lasting anosmia

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

Aducanumab: What to Know If You Prescribe

Recommendations may change when trial data are published

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

Better Air, Better Brains

Reducing air pollution tied to lower dementia risk, slower cognitive decline

Illustration of a brain shaped maze.

Drug Overdoses Spike; Shock Therapy Effective; Psychiatrist Charged for 'Pill-Mill'

News and commentary from the psychiatry world

A stressed looking senior woman next to a bottle of Nuplazid (pimavanserin) capsules.

Staying on Pimavanserin Cut Dementia-Related Psychosis Relapse

However, late-stage trial couldn't separate efficacy in dementia subtypes

A mature man laying on a couch winces from abdominal pain.

New-Onset IBD and IL-17 Inhibitors: What Is the Risk?

Underlying inflammatory disease severity should be taken into account

A senior woman talks on her smartphone at home.

Phone Calls Spot Early Alzheimer's

Predictive model identified vocal features of dementia patients from everyday speech

FDA ADCOMM roxadustat over a computer renering of chronic kidney disease.

Safety Concerns Turn FDA Panel Thumbs Down for Novel CKD-Anemia Drug

Advisory committee rejected oral anemia drug for dialysis and non-dialysis patient populations

The vial and packaging of Aduhelm (aducanumab) for injection with blurred prescribing information in the background.

Alzheimer's Aducanumab Prescribing Information Changes

"We as neurologists need a strategy to advise our patients," experts say

A chart showing estrogen levels in a female silhouette from age 25-80

Alzheimer's Biomarkers Tied to Endogenous Estrogen Exposure in Women

Longer reproductive period linked to amyloid, p-tau in cognitively normal older women

A screenshot of a TikTok video with Kelly Morris with the caption: I鈥檇 unplug your vent to charge my cell phone.

Nurse Suspended Over TikTok Videos About Patients

Only thing hurt in her posts were "people's feelings," nurse said

A mature person with Down syndrome draws in an activity book.

APOE Gene Influences Alzheimer's Symptoms, Biomarkers in Down Syndrome

Earlier Alzheimer's changes seen in APOE4 carriers

A young female healthcare worker in blue scrubs holding a brochure speaks to a concerned looking senior woman.

Give All Patients a Voice in Their Care

The pandemic has emphasized the importance of access to advance care planning

A computer rendering of the release of cytokines.

Two Inflammatory Proteins Linked With Slower Cognitive Decline

Surprise finding ties plasma cytokine levels with Alzheimer's biomarkers and cognition

A computer rendering of a Trulicity (dulaglutide) auto injector over a photo of a twisted sheet.

'Modest' Erectile Dysfunction Benefit With GLP-1 Agonist

Dulaglutide didn't improve pre-existing symptoms, but did prevent some new cases

A 3 layer pill with ixazomib, lenalidomide, and dexamethasone etched into it over a microscopy of multiple myeloma.

No Survival Benefit With All-Oral Regimen for Relapsed/Refractory Myeloma

Prolonging PFS a positive, as advances make OS improvement harder to achieve

A low angle view of a senior woman holding her bandaged wrist.

Does Grandma Need Surgery for That Broken Wrist?

Randomized trial findings should help in decision-making

EHA over a computer rendering of red blood cells flowing through an artery

Fixed-Duration, All-Oral Regimen Slows CLL Progression

Near-80% reduction in PFS hazard with ibrutinib-venetoclax versus obinutuzumab-chlorambucil

A microscopy of Neurofibrillary tangles in the Hippocampus of an old person with Alzheimer-related pathology.

Alzheimer's Tau Vaccine Shows Immune Response, Safety

Exploratory, post hoc analyses hint at plasma NfL changes, and in some, slower cognitive decline

SLEEP over a conceptual image of dreaming: a woman in a bed floating in the clouds with birds.

Trouble Falling Asleep Predicts Later Cognitive Impairment

Depression and vascular disease may play roles

A senior woman visits with her female gynecologist.

Most Older Women Do Not Meet Criteria to Stop Cervical Cancer Screening

Inadequate screening in middle age, lack of medical record documentation highlighted

A photo of a traditional British breakfast with sausage, fried eggs, ham, toast, beans, a tomato, and mushrooms.

An Unhealthy Diet Feeds Into Clonal Hematopoiesis

Can diet mitigate the CVD risk of this age-related genetic phenomenon?

$An x-ray image of a persons arm with fractured radius and ulna$

Are All Types of Fractures Predictive of Osteoporosis?

Researchers investigate both traumatic, non-traumatic types

A female nurse at a computer workstation reviews a bone mineral density scan of her mature male patient

With Supplements, ADT in Prostate Cancer of Little Threat to Bone Density

Study suggests calcium/vitamin D alone sufficient for long-duration therapy

A lateral x-ray of a mans head with electrodes in place for deep brain stimulation

How Long Do Deep Brain Stimulation Benefits Last?

Parkinson's patients saw continued improvement in motor symptoms, quality of life

A photo collage of a wall clock and a portrait of a senior man staring into space and disintegrating into particles.

Cognitive Clock Predicts Brain Health

Brain age forecasts outcomes better than chronological age

A computer rendering of phosphorylation of tau proteins

Simple Tool Predicts Individual Alzheimer's Risk

Blood and quick cognitive tests boost accuracy to 90%

AACE over a computer rendering of a woman with her pituitary and thyroid glands highlighted.

High Frequency Spinal Stimulation Succeeds in Diabetic Neuropathy

Pain relief was significant and durable in SENZA-PDN trial

AACE over a computer rendering of a woman with her pituitary and thyroid glands highlighted.

Two-Agent Osteoporosis Treatment Boosts BMD

3D DXA images shows separate assessments of trabecular and cortical bone in ACTIVExtend trial

AACE over a computer rendering of a woman with her pituitary and thyroid glands highlighted.

COVID-19 in Diabetes: What Mediates Risk?

Certain clinical factors tied to higher chance of severe infection

A photo of Daniel Gibbs, MD, PhD, next to his book A Tattoo on My Brain

A Neurologist Faces His Alzheimer's Disease

"I'm in the ring with the tiger," says Daniel Gibbs

A blue gloved hand holds a test tube of blood labeled Testosterone - Test over a form with results showing low testosterone.

Low Testosterone Could Be Bad News in COVID-19

In small study, men with low levels were more likely to have severe illness

Breast Cancer Screening During COVID Reveals Inequities

Vinay Prasad, MD, MPH, discusses new findings and his takeaway

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