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Gastroenterology

News, opinions and meeting coverage in gastroenterology.

Year in Review: Inflammatory Bowel Disease

β€” "Top down" vs "step up" therapy, FDA actions, rethinking placebos, and new tulisokibart data

2024 YEAR IN REVIEW IBD

Latest in Gastroenterology

Crohn's Disease, Ulcerative Colitis Linked to Pesticide Exposure

Elevated risk of IBD for people exposed to environmental pollutants in the prior decade

Nov 21, 2024
FDA Approves Zanidatamab for Biliary Tract Cancer

New antibody indicated for previously treated, unresectable or metastatic HER2-positive disease

Nov 21, 2024
Novel Therapy Reduced Liver Fat, Improved Fibrosis in MASH

Liver fat reductions were sustained for up to a year with the thyroid hormone receptor agonist

Nov 21, 2024
'A Watershed Moment': GLP-1 Drug Succeeds in Late-Stage MASH Trial

First positive phase III study for a GLP-1 agonist in chronic liver disease

Nov 20, 2024
Novel Therapy Reduced Liver Fat, Improved Fibrosis in MASH

Liver fat reductions were sustained for up to a year with the thyroid hormone receptor agonist

'A Watershed Moment': GLP-1 Drug Succeeds in Late-Stage MASH Trial

First positive phase III study for a GLP-1 agonist in chronic liver disease

Gastroenterology Case Studies

Child Develops Voluminous Diarrhea After Amoxicillin

Discordant test results complicate diagnosis of suspected C. difficile

 A photo of a fecal sample container.
Elderly Farmer Experiences Strange Abdominal Rash and GI Symptoms

Moral of the story: don't walk barefoot in the fields

A photo of a senior woman laying in bed grimacing and holding her stomach.
Case Shows Danger of Gallstone Ileus in Patients Over 65

Clinicians found CT scan to be best diagnostic tool

 A photo of a senior woman outdoors doubled over in pain.

More in Gastroenterology

Tapered Steroid Dosing Safe, Effective in Severe Alcohol-Associated Hepatitis

Notably, tapering reduced the risk of infection compared with a fixed dose

Nov 20, 2024
AASLD over a photo of San Diego Convention Center in San Diego, CA.
New MELD Model Improves Access to Liver Transplant for Women

A greater proportion of women on the waitlist and undergoing transplant since adoption

Nov 19, 2024
AASLD over a photo of San Diego Convention Center in San Diego, CA.
Immunotherapy Shows Promise in Downstaging Liver Tumors Prior to Transplant

78% of patients in prospective study had tumor downstaging with immune checkpoint inhibitors

Nov 19, 2024
AASLD over a photo of San Diego Convention Center in San Diego, CA.
Study: Statins Mitigate Heart Risks From JAK Inhibitors

Is this the final finding from ORAL Surveillance? Don't count on it.

Nov 18, 2024
ACR over a photo of Walter E. Washington Convention Center in Washington, D.C.
Fecal Therapy Shows Survival Benefit in Severe Alcoholic Hepatitis

Improved markers of disease severity as well in small trial of steroid-ineligible patients

Nov 18, 2024
AASLD over a photo of San Diego Convention Center in San Diego, CA.
Alarming Surge in Alcohol-Related Liver Transplants in Younger Adults

Targeted preventive strategies needed, especially for younger women, researchers say

Nov 14, 2024
A photo of surgeons performing a liver transplant.
GLP-1 Drugs Could Help People With Alcohol Use Disorder

Real-world data suggested semaglutide, liraglutide reduced AUD-related hospitalizations

Nov 13, 2024
A photo of a man holding a semaglutide injection pen.
FDA Rejects Full Approval of Liver Disease Drug

Agency's decision on obeticholic acid in PBC follows negative advisory committee meeting

Nov 12, 2024
A photo of bottles of Ocaliva tablets over a computer rendering of the gallbladder with bile duct and biliary tree.
Do GLP-1 Agonists Really Need to Be Stopped Before Endoscopy?

Meta-analysis suggests 24-hour clear liquid diet works to avoid aspiration, even with GLP-1s

Nov 05, 2024
ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.
ACG Roundup: Young-Onset Barrett's Esophagus on the Rise

Selected highlights from the 2024 American College of Gastroenterology annual meeting

Nov 04, 2024
ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.
Rifaximin Reduced Overt Hepatic Encephalopathy Recurrence Over Lactulose

Rifaximin also reduced mortality, but its high cost may be a barrier

Nov 01, 2024
ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.
AI Colonoscopies: More Benign Lesion Removals, Potentially Higher Costs

At scale, the benefits of AI-assisted colonoscopy may not always outweigh the costs

Oct 31, 2024
ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.
Novel Drug Improved Symptoms in Eosinophilic Esophagitis

Monoclonal antibody cendakimab also reduced eosinophils compared with placebo

Oct 30, 2024
ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.
Colorado Teen Fights Kidney Failure After Eating McDonald's Quarter Pounders

Deadly E. coli outbreak has been tentatively traced to contaminated onions

Oct 30, 2024
A selfie of Brittany Randall and her daughter Kamberlyn Bowler in Grand Junction Colorado in the summer of 2024.
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