After Rejection, Tenapanor for Kidney Disease Faces FDA's Outside Experts Drug's effect on serum phosphorus "small and of unclear clinical significance," say FDA reviewers Nov 15, 2022
Earlier Terlipressin May Be Better for HRS-AKI in Acute-on-Chronic Liver Failure More acute kidney injury reversals at 7 days and lower mortality with initiation at 12 hours Nov 07, 2022
Mixed Results With Alerts for AKI-Related Medications in Hospital EHR pings improved outcomes in those on PPIs, but lacked general clinical impact Nov 06, 2022
Stop RAS Inhibitors in Advanced CKD? STOP ACEi Trial Sheds Some Light Findings do not support discontinuation to improve kidney function, researchers say Nov 03, 2022
New HRS Drug Cuts Need for Renal Replacement Tx After Liver Transplant Follow-up data from CONFIRM trial show terlipressin benefit in key subgroup Oct 25, 2022
The ľ¹ÏÖ±²¥ Transplant Ecosystem Is Ripe for Reform Here are the policies and payment systems that need to change Oct 11, 2022
Salt Pills During Diuresis: Acute HF Patients Neither Helped Nor Harmed Small randomized trial challenges conventional thinking about sodium Oct 05, 2022
FDA Finally OKs First Drug for Hepatorenal Syndrome Pivotal trial data showed terlipressin nearly doubled reversal of the condition Sep 15, 2022
Age-Related Kidney Function Loss Differs Significantly by Gender Age- and sex-adjusted definitions of chronic kidney disease may be necessary, researchers say Aug 17, 2022
CDC: More Clots, Kidney Failure in Kids After COVID Post-COVID symptoms run the gamut for kids and teens Aug 05, 2022
Kidney Failure May Drive COVID Deaths in People With Sickle Cell Trait COVID-19 severity strongly linked with sickle cell anemia as well Jun 27, 2022
Transplant Success Without Immune Suppressive Drugs Did small pediatric case series achieve the "Holy Grail" of transplant medicine? Jun 15, 2022
Tirzepatide Reduced Albuminuria in T2D Patients With Heart Risk Subanalysis of SURPASS-4 trial compared the GLP-1/GIP agonist against insulin glargine Jun 06, 2022
Even With CKD, Patiromer Helped Heart Failure Patients Keep Hyperkalemia at Bay Promising findings from prespecified renal analysis of the DIAMOND trial Apr 09, 2022
COVID-Related AKI Chronically Hard on Kidneys More critically ill COVID patients developed CKD versus bacterial pneumonia patients Apr 08, 2022
Elderly Man Presents With Bradycardia and Chronic Kidney Dysfunction Consider BRASH syndrome Jan 31, 2022
Obesity More Common in Type 1 Diabetes Than Expected And this is putting the population at a higher risk for chronic kidney disease, researchers say Jan 26, 2022
Next Up in Drug Shortages: Potassium Chloride Healthcare providers facing a nationwide shortage of the intravenous formulation Dec 17, 2021
FDA OKs First Proteinuria Drug for IgA Nephropathy Supporting trial found budesonide lowered proteinuria by 34% when added to a RAS inhibitor Dec 16, 2021
FDA Panel Shoots Down Drug for Alport Syndrome CKD Flawed trial design, safety signals turned all thumbs down for bardoxolone Dec 09, 2021
Avacopan Helps Vasculitis Patients With Renal Impairment Wean Off Steroids Patients saw better eGFR recovery compared with prednisone Nov 08, 2021
Longer Steroid Course No Better for Young Kids With Nephrotic Syndrome Study compared 6-month course to standard 3-month therapy Nov 08, 2021
Steroids Cut Risk for Serious Renal Events in IgA Nephropathy Researcher says TESTING study findings support new KDIGO guidelines Nov 08, 2021
Injectable PH1 Therapy Also Effective in Advanced CKD Trial looked at patients with stages 3B through 5 chronic kidney disease Nov 07, 2021
More Good News for Empagliflozin in Patients With Heart Failure Slower renal function decline with SGLT-2 inhibitor in EMPEROR-Preserved trial Nov 06, 2021
Investigational Oral CKD-Anemia Agent Effective, Safe HIF-PHI daprodustat increased hemoglobin without hurting heart Nov 05, 2021
Diuretic Bolstered Blood Pressure Control in Advanced CKD But some safety signals did arise in 12-week trial Nov 05, 2021
Common Gene Variant May Predict Peritoneal Dialysis Outcomes Study also suggests that one dialysate type is better for carriers Oct 20, 2021
Antibiotics Used in Dialysis Patients Linked With Sudden Cardiac Death Should floxacins stay or should they go in these patients? Oct 20, 2021
Overdiagnosis of Kidney Disease; Severity of the Delta Variant Also this week in TTHealthWatch: Tight blood pressure control and COVID sequelae at 6 months Sep 04, 2021 podcast
Nonsteroidal MRA Drug Cuts Risks in Earlier Diabetic Kidney Disease Urine screening urged after trial shows benefit of treating cases with preserved kidney function Aug 29, 2021
Kidney Disease No Barrier to Effient Benefit in ACS Trial analysis supports superiority over ticagrelor regardless of eGFR Aug 23, 2021
ľ¹ÏÖ±²¥ Transplant Outcomes Improved Over Past Quarter-Century Patient and graft survival rates have increased since 1996 Aug 18, 2021
Pot Smokers Face Distinct Risks After Coronary Procedures But could marijuana use be associated with fewer cases of acute kidney injury? Aug 16, 2021
SGLT2 Inhibitor Adds Years of Life to Patients With Heart Failure DAPA-HF group makes projections as long-term data are lacking Jul 28, 2021
Dexcom's CGM Interoperability Expands; Warfarin and Osteoporosis; Maine Bans PFAS News and commentary from the endocrinology world Jul 18, 2021
Safety Concerns Turn FDA Panel Thumbs Down for Novel CKD-Anemia Drug Advisory committee rejected oral anemia drug for dialysis and non-dialysis patient populations Jul 16, 2021
'Acceptable' Lead in Drinking Water May Still Be Harmful to Patients With CKD No safe amount of lead in water for those with kidney disease, researchers warn Jul 15, 2021
Finerenone OK'd for Slowing Kidney Disease in T2D Drug also indicated for cardiovascular event risk reduction Jul 09, 2021
