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Nephrology

CHF

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Metformin, Lifestyle Changes Fail to Reduce Afib Burden

Standard of care prevails in single-center trial

Nov 20, 2024
AHA over a photo of McCormick Place Convention Center in Chicago, IL.
Potassium Binder Cuts Hyperkalemia Risk in HF Patients on Spironolactone

More patients taking sodium zirconium cyclosilicate achieved normokalemia vs placebo recipients

Nov 20, 2024
AHA over a photo of McCormick Place Convention Center in Chicago, IL.
Sacubitril/Valsartan Curbs Cardiotoxicity From Chemotherapy

Benefit shown in trial of patients flagged for high risk of cardiotoxicity

Nov 20, 2024
AHA over a photo of McCormick Place Convention Center in Chicago, IL.
Nasal Spray Diuretic Shows Potential for Heart Failure in Trial of Healthy Adults

Intranasal bumetanide demonstrated safety, bioequivalence with its oral and IV counterparts

Nov 19, 2024
AHA over a photo of McCormick Place Convention Center in Chicago, IL.
Novel CRISPR-Cas9-Based Promising in ATTR Cardiomyopathy

One-time treatment with nexiguran ziclumeran tied to decline in serum TTR levels in phase I trial

Nov 17, 2024
AHA over a photo of McCormick Place Convention Center in Chicago, IL.
Tirzepatide Officially Puts GLP-1 Meds on the Map for Obesity-Related Heart Failure

SUMMIT trial able to show clinical benefit beyond quality-of-life improvement

Nov 16, 2024
AHA over a photo of McCormick Place Convention Center in Chicago, IL.
Inching Toward a Blood Test for Hypertrophic Cardiomyopathy

Researchers try to address challenge of distinguishing HCM from other cardiomyopathies

Nov 11, 2024
 A photo of vials of blood laying on a test form.
Tricuspid Valve Replacement Finds Surer Footing With TRISCEND II's 1-Year Report

Evoque device helped outcomes in severe tricuspid regurgitation, with some safety caveats

Oct 31, 2024
TCT over a photo of Walter E. Washington Convention Center, in Washington, D.C.
No Kidney Benefit With Finerenone in Heart Failure Patients

Anti-mineralocorticoid agent reduced albuminuria, but not eGFR-based kidney outcome

Oct 28, 2024
ASN over a photo of San Diego Convention Center in San Diego, CA.
Safety Data Favor Diuretic Strategy Triggered by Cardiac Monitoring Alerts in HF

Effectiveness of this personalized approach now under investigation

Oct 11, 2024
A photo of an implantable loop recorder in the palm of a man's hand.
Elamipretide for Barth Syndrome Survives FDA Advisory Vote

Panelists acknowledge difficulty generating stronger data in ultra-rare disease

Oct 11, 2024
FDA ADCOMM elamipretide hydrochloride injection over a computer rendering of mitochondria.
FDA Reviewers Cast Doubt on Drug Candidate for Barth Syndrome

Agency appears unswayed by mitochondria-targeting drug for rare cardioskeletal disease

Oct 09, 2024
FDA ADCOMM elamipretide hydrochloride injection over a computer rendering of mitochondria.
Metabolic Accelerator Shows Promise for Weight Loss Side of Obesity-HFpEF Equation

Benefit in symptoms, functional outcomes remains to be seen for HU6

Oct 02, 2024
HFSA over a computer rendering of the human heart.
Mavacamten Shows Promise in Heart Failure With Normal to Supranormal EF

Cardiac myosin inhibitor linked to improvements in biomarkers in small study

Sep 30, 2024
HFSA over a computer rendering of the human heart.
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