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News, opinions and meeting coverage in psychiatry.

The Spravato nasal spray applicator

Spravato Debate Still Rages

Journal airs questions about efficacy data, potential for harm

An illustration of two depressed people in front of pills in bottles and blister packs

How Variable are Patient Responses to Antidepressants?

Certain classes show less predictability than others

A portrait of a blurred man

Akathisia: A Deadly Imposter

Be on the lookout for it

Illustration of a brain shaped maze.

Magic Mushrooms Ease Cancer Anxiety; Olanzapine/Samidorphan NDA Accepted

News and commentary from the psychiatry world

Photo of the White House.

Trump Administration Touts Mental Health Accomplishments

Speakers offer praise for more aggressive involuntary commitment

A black and white image of a multi-exposure image depicting a woman鈥檚 emotional struggles

Parkinson's Risk Higher in People With Bipolar Disorder

Analysis looks at more than 4 million people

PSYCH CONGRESS over a photo of the San Diego Convention Center in San Diego, CA

Novel Combo Tx Shows Durable Antipsychotic Effects

Almost half of patients with schizophrenia deemed PANSS responders with samidorphan/olanzapine

Illustration of a brain shaped maze.

Sarcosine for Schizophrenia; Abilify Lawsuit; Rural America Suffering

News and commentary from the psychiatry world

A photo of three inmates in suicide prevention clothing in a prison setting

What Really Went Wrong at Jeffrey Epstein's Jail

It wasn't just the guards' failure, suggests jail doctor Jeffrey Keller

A face icon split down the middle, one half sad, one half happy.

Parkinson's Tied to Bipolar Disorder

Trends emerge even after adjusting for mood stabilizers

Illustration of a brain all in green.

'13 Reasons Why' Suicide Spike; Sleeping Pill Warning; Bipolar Genes

News and commentary from the psychiatry world

New Depression, ADHD Drugs OK'd; DMT Microdosing; Bitcoin Addiction?

News and commentary from the psychiatry world

Cat Poop and Schizophrenia; Cannabis for a 4-Year-Old

News and commentary from the psychiatry world

Comorbidities 'Pervasive' Within Mental Disorders

Increased risk for second disorders seen early and beyond 15 years

Antipsychotics Linked to Greater Risk of Death for Youths

Most deaths were unexpected, suggesting side effects but with many limitations

Depressed Man Refuses Life-Saving Pacemaker; Now What?

Determining competency and when physicians should intervene

Nitrate-Cured Meats Linked to Manic Episodes

Meat sticks, jerky showed biggest association

Family History Predictor of Psychiatric Illness Postpartum

Increased risk tied to several psychiatric conditions experienced among first-degree relatives

Potentially Fatal Immune Reactions to Lamotrigine Draw FDA Warning

Eight serious events including one death since drug was approved in 1994

Doctor's Widow on Anti-Suicide Crusade

ZDoggMD interviews Janae Sharp, whose physician husband committed suicide

FDA Approves New Valbenazine Formulation (Neurocrine Biosciences)

One 80-mg capsule once daily for tardive dyskinesia

Quelling Overdiagnosis of Bipolar Disorder in Kids

New DSM-5 category may better capture the actual condition

AMA Urges Weapons Be Limited in Hospitals

Resolution aimed at units housing mental health patients

FDA Warns of Skin Reaction With Olanzapine

Zyprexa and Symbyax among products to get warning label

FDA Warning: Abilify Tied to Impulse Control Problems

In rare cases, may prompt "uncontrollable urges"

New Drug Eases Tardive Dyskinesia in Pivotal Trial

Tremors related to treatment for schizophrenia quieted by VMAT2 inhibitor

Zyprexa: Also a Pain Med?

Meta-analysis suggests analgesic effect for antipsychotic drug

Can Antidepressants Trigger Mania?

SSRIs, venlafaxine associated with mania, but causal relationship uncertain

APA Meeting Highlights Mental Health Biology

NEW YORK CITY -- The biological basis for normal and abnormal mental function is emerging as a dominant theme in psychiatry research, and the American Psychiatric Association annual meeting that starts here Saturday won't be an exception.

APA Leaders Defend New Diagnostic Guide

SAN FRANCISCO -- The fifth edition of the "psychiatrist's bible" was officially released here in all its 947-page glory, with its developers offering a spirited rebuttal to their critics.

Jesse Jackson, Jr. Responding to Bipolar Therapy

After months of silence from his office about his absence from Congress, the Mayo Clinic has announced that Rep. Jesse Jackson, Jr., (D-Ill.) is being treated at the facility for bipolar disorder.

DSM-5: What's In, What's Out

PHILADELPHIA -- Reports here provided what may be the last public update on DSM-5, the next edition of American psychiatry's diagnostic guide, before it is formally released in May 2013.

Most DSM-5 Revisions Pass Field Trials

PHILADELPHIA -- Field trials of proposed new diagnostic criteria for many mental disorders showed that, for the most part, they were at least adequately reliable.

Tardive Drug Effect Is Often Permanent

NEW ORLEANS -- Only about one patient in eight who develops tardive syndromes as a result of an antipsychotic or other drug therapy ever fully recovers, a researcher said here.

FDA Panel Split Over Inhaled Antipsychotic

WASHINGTON -- An FDA advisory panel punted on the question of approval for an inhaled version of the antipsychotic drug loxapine (Adasuve) to treat agitation in bipolar and schizophrenic patients, despite the risk for respiratory side effects.

Side Effects of Loxapine Aerosol Raise FDA Concerns

WASHINGTON -- Although staccato loxapine (Adasuve) appears to be effective in calming schizophrenic and bipolar patients, concerns remain about the drug's pulmonary side effects, according to a review by FDA staff members.

Mild Mania Often Accompanies Major Depression

A high proportion of people with major depression may actually have a "hidden" form of bipolar disorder, according to a population-based study.

Ziprasidone Okayed for Bipolar Disorder

The FDA has approved another antipsychotic agent -- ziprasidone (Geodon) -- for maintenance treatment of bipolar I disorder as an adjunct to lithium or valproate.

Neurochemical May Underlie Lack of Motivation in Psychosis

CAMBRIDGE, England -- The lack of motivation characteristic of schizophrenia and other psychoses may not be a result of long-term treatment or institutionalization, researchers here suggested.

APA: Co-Morbid ADHD in Bipolar Adults May Respond To Non-Stimulants

SAN DIEGO -- When attention deficit hyperactivity disorder meets bipolar disorder in an adult, the diagnosis is hard and the course is poorly understood but the co-morbidity appears to exacerbate matters, researchers said here.

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