Tirzepatide Tops Semaglutide for Weight Loss in Head-to-Head Trial, Eli Lilly Says Dual GLP-1/GIP drug yielded an average 47% greater relative weight loss compared to semaglutide Dec 04, 2024
Makers of Sickle Cell Disease Gene Therapy to Participate in Payment Model, CMS Says Outcomes-based model designed to improve access to pricey treatments Dec 04, 2024
New Rule Allows HIV-Positive Organ Transplants Previously, such transplants could be done only as part of research studies Nov 26, 2024
Many Drinkers Cut Back After Starting Obesity Meds, Study Finds In WeightWatchers study, 45% decreased their alcohol use after initiating a weight-loss drug Nov 26, 2024
CGM Uptake Very Low for Vulnerable Diabetes Populations But how to achieve equitable use remains "complicated," says expert Nov 22, 2024
GLP-1 Use Prior to Surgery: Analyzing the Updated Guidance Balancing aspiration risk with the consequences of medication discontinuation Nov 20, 2024
Metformin, Lifestyle Changes Fail to Reduce Afib Burden Standard of care prevails in single-center trial Nov 20, 2024
Potassium Binder Cuts Hyperkalemia Risk in HF Patients on Spironolactone More patients taking sodium zirconium cyclosilicate achieved normokalemia vs placebo recipients Nov 20, 2024
Sacubitril/Valsartan Curbs Cardiotoxicity From Chemotherapy Benefit shown in trial of patients flagged for high risk of cardiotoxicity Nov 20, 2024
Nasal Spray Diuretic Shows Potential for Heart Failure in Trial of Healthy Adults Intranasal bumetanide demonstrated safety, bioequivalence with its oral and IV counterparts Nov 19, 2024
Over 50% of U.S. Adults Qualify for Ozempic, Wegovy Most are eligible for weight management indication Nov 18, 2024
Multimarker Urine Test Promises to Improve Lupus Nephritis Diagnosis, Prognosis Accuracy above 85% in early testing -- far better than proteinuria and biopsy Nov 18, 2024
Novel CRISPR-Cas9-Based Promising in ATTR Cardiomyopathy One-time treatment with nexiguran ziclumeran tied to decline in serum TTR levels in phase I trial Nov 17, 2024
Tirzepatide Officially Puts GLP-1 Meds on the Map for Heart Failure Benefit SUMMIT trial able to show clinical benefit beyond quality-of-life improvement Nov 16, 2024
Intensive Blood Pressure Control Benefits People With Type 2 Diabetes Too BPROAD trial replicates SPRINT trial findings in diabetes population in China Nov 16, 2024
Multiple Chronic Conditions and Death; Diabetes Treatment for Gout Also in TTHealthWatch: frailty as a predictor of dementia Nov 16, 2024 podcast
GLP-1 Drugs Could Help People With Alcohol Use Disorder Real-world data suggested semaglutide, liraglutide reduced AUD-related hospitalizations Nov 13, 2024
ObesityWeek Roundup: Patients More Likely to Ration Weight-Loss Drugs Plus: oral semaglutide outcomes and incident hypertension in teens on GLP-1 drugs Nov 11, 2024
Inching Toward a Blood Test for Hypertrophic Cardiomyopathy Researchers try to address challenge of distinguishing HCM from other cardiomyopathies Nov 11, 2024
Who Needs a Defibrillator After MI? FDA Recs on Inferior Vena Cava Filters Also in TTHealthWatch: early sugar exposure, hypertension, and diabetes Nov 09, 2024 podcast
Nurse's Death Tied to GLP-1 Drug; Research Monkey Jailbreak; Congressman Has Cancer Health news and commentary gathered by ľֱ staff Nov 08, 2024
Zepbound's Weight Loss, Cardiometabolic Benefits Hold Up at 3 Years Nearly all participants in SURMOUNT-1 avoided diabetes with the GLP-1/GIP receptor agonist Nov 07, 2024
Early-Life Sugar Restriction Reduced Diabetes, Hypertension Risk Diagnoses were also delayed the longer sugar was restricted Nov 06, 2024
Do GLP-1 Agonists Really Need to Be Stopped Before Endoscopy? Meta-analysis suggests 24-hour clear liquid diet works to avoid aspiration, even with GLP-1s Nov 05, 2024
FDA Panel Rejects SGLT1/2 Inhibitor for Type 1 Diabetes Data too uncertain to support sotagliflozin in subset with chronic kidney disease, advisors say Nov 01, 2024
Tricuspid Valve Replacement Finds Surer Footing With TRISCEND II's 1-Year Report Evoque device helped outcomes in severe tricuspid regurgitation, with some safety caveats Oct 31, 2024
Ex-Gov. May Face Charges Over COVID; Autism Dx Up 175%; Can Fasting Help Kidneys? Health news and commentary gathered by ľֱ staff Oct 31, 2024
FDA Staff Not Quite Sold on Sotagliflozin for T1D Patients With CKD SGLT1/SGLT2 inhibitor has another shot in T1D, but now in more narrow patient population Oct 30, 2024
ASA Advises No Longer Holding GLP-1 Agents Prior to Surgery for Most Patients New guidance replaces earlier rec of a 1-week and 1-day hold of injectable and oral GLP-1 agents Oct 30, 2024
Colorado Teen Fights Kidney Failure After Eating McDonald's Quarter Pounders Deadly E. coli outbreak has been tentatively traced to contaminated onions Oct 30, 2024
Wegovy Cut Albuminuria by Half in Non-Diabetic CKD However, 24 weeks of the GLP-1 had no impact on eGFR Oct 29, 2024
Early AKI Care Recommendations Did Not Improve Patient Outcomes Personalized recs were made by team of physicians and pharmacists within an hour of diagnosis Oct 29, 2024
SGLT2 Inhibitor Carry-Over Benefits Last How Long? Trial follow-up defines the need for long-term treatment in protecting the kidneys and heart Oct 29, 2024
Kidney Disease Genetic Risk Common in West Africans Observational study points to genetic risk allele dose-response Oct 29, 2024
No Kidney Benefit With Finerenone in Heart Failure Patients Anti-mineralocorticoid agent reduced albuminuria, but not eGFR-based kidney outcome Oct 28, 2024
Complement Inhibitor Shows Promise for Rare Kidney Disorder Ravulizumab reduced proteinuria, stabilized eGFR in IgA nephropathy Oct 28, 2024
Interim ALIGN Data: Atrasentan Cuts Proteinuria in IgA Nephropathy Surrogate endpoint of urinary protein-to-creatinine ratio "widely considered to be predictive" Oct 27, 2024
