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Nephrology

News, opinions and meeting coverage in nephrology.

FDA APPROVED Generic liraglutide (Victoza) over a photo of a man self-injecting diabetes medication.

First Generic of Once-Daily GLP-1 Injection Approved for Diabetes

Generic liraglutide approved at dosage for type 2 diabetes only

A computer rendering of a transparent body with diseased kidneys highlighted.

Study Underscores Caution for NSAID Use in Pregnancy

Observational study details kidney disease risk for children after gestational exposure

A photo of a Mounjaro injection pen sitting on a box of four.

FDA Says Compounded Tirzepatide Must Exit the Market

Compounders only have 2 to 3 months left to copy injectable

A photo of glasses of red and white wine.

Cardiovascular Protection Tracks With Wine Intake, Now Provable With Urinary Marker

Biomarker of wine consumption believed to reduce misclassification and bias in study

A photo of surgeons holding the pig kidney.

Woman Dialysis-Free After Receiving Gene-Edited Pig Kidney

Clinical trials of xenotransplantation expected to kick off next year

A photo of surgeons removing a kidney from a living donor.

How 'General Hospital' Missed a Chance to Promote Living Organ Donation

A recent storyline offered a negative spin

ASHP over a photo of Ernest N. Morial Convention Center in New Orleans, LA.

Newer Diabetes Drugs Still Under-Prescribed in High-Risk Patients

Cost, insurance coverage likely play outsized role

The FDA Hasn't Inspected This Drug Factory After 7 Recalls for the Same Flaw

With a potentially deadly recall, case highlights shortcomings in overseas drug manufacturing

Medical Assistance in Dying; Health Benefits of Chocolate?

Also in TTHealthWatch: depression treatment after positive screening in primary care

A photo of a woman self-injecting in her thigh with a semaglutide pen.

A New Fad: Microdosing Ozempic

Why it's unlikely to help most people

A photo of a nurse holding a bag of red blood cells.

Generous Blood Transfusions Not Beneficial for Some With Burst Brain Aneurysms

SAHARA rounds out this year's notable trials on blood transfusions in critically ill patients

ASH over a photo of San Diego Convention Center

Benefits of Transplant for Pediatric Sickle Cell Disease Add Up a Decade Later

Better disease outcomes, measures of cognition, and quality-of-life vs standard care, study finds

A photo of a woman holding a smartphone which is displaying an incoming call.

Empathetic Phone Calls Help Vulnerable Diabetes Patients Lower HbA1c

Social support may be key to improving glycemic control, experts say

AES over a photo of Los Angeles Convention Center

Could a Hypertension Drug Protect Against Post-Stroke Epilepsy?

Observational study suggests one antihypertensive class might be preventive

Are GLP-1 Drug Holidays a Risk Worth Taking?

Experts weigh in on weight regain, cardiometabolic fallout, and the future of tailored care

ASH over a photo of San Diego Convention Center

GLP-1 Drugs Tied to Reduced Risk of Dangerous Blood Clots

20% lower risk of VTE observed in large retrospective study of diabetes patients

A computer rendering of atherosclerosis.

Women's CVD Risk Calculations Barely Budge When Sex-Specific Variables Are Included

Existing models improved only slightly after accounting for certain female risk factors

A screenshot of Bernie Sanders speaking during this hearing.

FDA Panned at Senate Hearing for Failure to Address Diabetes, Obesity Epidemics

Agency has failed to hold food manufacturers accountable, said Sen. Bernie Sanders

An ophthalmoscope image of an eye with diabetic retinopathy.

Empagliflozin Linked to Lower Risk of Diabetic Retinopathy Progression

But the drug didn't appear to lower the risk of incident nonproliferative diabetic retinopathy

Untangling GLP-1 Risks: Are Side Effects Overblown?

Experts tackle myths, data bias, and game-changing outcomes of obesity drugs

A photo of a broken bar of dark chocolate.

New Study Teases Out Chocolate and Diabetes Connection

Eating more dark chocolate was associated with a lower risk of type 2 diabetes

A photo of a tirzepatide (Zepbound) injection pen over an out of focus photo of a barbell wrapped in a measuring tape and a s

Tirzepatide Tops Semaglutide for Weight Loss in Head-to-Head Trial, Eli Lilly Says

Dual GLP-1/GIP drug yielded an average 47% greater relative weight loss compared to semaglutide

A computer rendering of sickle cells in the blood flow.

Makers of Sickle Cell Disease Gene Therapy to Participate in Payment Model, CMS Says

Outcomes-based model designed to improve access to pricey treatments

The advertisement for this Instagram Live event.

IG Live December 2: The Weight of Wegovy

How GLP-1 drugs are reshaping medicine

Surgical instruments and supplies lay on a table during a kidney transplant surgery.

New Rule Allows HIV-Positive Organ Transplants

Previously, such transplants could be done only as part of research studies

Pouring whisky away down the sink.

Many Drinkers Cut Back After Starting Obesity Meds, Study Finds

In WeightWatchers study, 45% decreased their alcohol use after initiating a weight-loss drug

Photo of a person with gout receiving urate lowering therapy.

Study: CKD Not Worsened With Gout Treatment

It might even help, researchers say

A photo of a woman taking a reading with her continuous glucose monitor.

CGM Uptake Very Low for Vulnerable Diabetes Populations

But how to achieve equitable use remains "complicated," says expert

A photo of an injection pen.

GLP-1 Use Prior to Surgery: Analyzing the Updated Guidance

Balancing aspiration risk with the consequences of medication discontinuation

AHA over a photo of McCormick Place Convention Center in Chicago, IL.

Metformin, Lifestyle Changes Fail to Reduce Afib Burden

Standard of care prevails in single-center trial

AHA over a photo of McCormick Place Convention Center in Chicago, IL.

Potassium Binder Cuts Hyperkalemia Risk in HF Patients on Spironolactone

More patients taking sodium zirconium cyclosilicate achieved normokalemia vs placebo recipients

AHA over a photo of McCormick Place Convention Center in Chicago, IL.

Sacubitril/Valsartan Curbs Cardiotoxicity From Chemotherapy

Benefit shown in trial of patients flagged for high risk of cardiotoxicity

AHA over a photo of McCormick Place Convention Center in Chicago, IL.

Nasal Spray Diuretic Shows Potential for Heart Failure in Trial of Healthy Adults

Intranasal bumetanide demonstrated safety, bioequivalence with its oral and IV counterparts

AHA over a photo of McCormick Place Convention Center in Chicago, IL.

Over 50% of U.S. Adults Qualify for Ozempic, Wegovy

Most are eligible for weight management indication

ACR over a photo of Walter E. Washington Convention Center in Washington, D.C.

Multimarker Urine Test Promises to Improve Lupus Nephritis Diagnosis, Prognosis

Accuracy above 85% in early testing -- far better than proteinuria and biopsy

AHA over a photo of McCormick Place Convention Center in Chicago, IL.

Novel CRISPR-Cas9-Based Promising in ATTR Cardiomyopathy

One-time treatment with nexiguran ziclumeran tied to decline in serum TTR levels in phase I trial

AHA over a photo of McCormick Place Convention Center in Chicago, IL.

Tirzepatide Officially Puts GLP-1 Meds on the Map for Heart Failure Benefit

SUMMIT trial able to show clinical benefit beyond quality-of-life improvement

AHA over a photo of McCormick Place Convention Center in Chicago, IL.

Intensive Blood Pressure Control Benefits People With Type 2 Diabetes Too

BPROAD trial replicates SPRINT trial findings in diabetes population in China

Multiple Chronic Conditions and Death; Diabetes Treatment for Gout

Also in TTHealthWatch: frailty as a predictor of dementia

A photo of a man holding a semaglutide injection pen.

GLP-1 Drugs Could Help People With Alcohol Use Disorder

Real-world data suggested semaglutide, liraglutide reduced AUD-related hospitalizations

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