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News, opinions and meeting coverage in nephrology.

A computer rendering of viruses in a transparent kidney.

Acute Kidney Injury Outcomes Better When It's Due to COVID, Study Finds

"Survivors of COVID-AKI appear to be a resilient population," say researchers

A photo of the Prolia auto injector and packaging.

FDA Slaps Boxed Warning on Osteoporosis Drug

Denosumab can cause severe hypocalcemia in patients with advanced CKD, agency finds

A computer rendered cutaway of a spine affected by osteoporosis

Calcium Levels Quickly Become Critical for Many Denosumab-Treated Women on Dialysis

New findings led to boxed warning on drug's labeling for advanced CKD patients

A photo of a senior woman sitting on her couch and talking on the phone.

Telehealth, Default Orders Show Promise in Palliative Care

Telecare improved quality of life for people with chronic illnesses

A photo of a senior woman laying in a hospital bed while receiving hemodialysis.

Top Insomnia Treatments Offer Little Relief for Dialysis Patients

CBT, trazodone outcomes were "surprising"

Go Vegetarian to Avoid COVID? Making Dialysis Centers Work Better

Also in TTHealthWatch: diagnostic errors among hospitalized patients

A computer rendering of a transparent body with the kidneys highlighted.

In Acute Kidney Disease, SGLT2 inhibitors Were All-Around Protective

Risk of all-cause mortality, MAKE, and MACE were significantly reduced

A photo of a female physician discussing a body mass index chart with her teen male patient.

Teens' High BMI Tied to Early Chronic Kidney Disease

"Enormous" risk increase seen in the highest BMI categories

A photo of a kidney model and urine specimen in front of an out of focus female physician talking to her pregnant patient

Kidney Disease in Pregnancy Often Overlooked for Care

These women had less nephrology care prior to end-stage disease onset

A photo of boxes of Kerendia tablets.

Quick Albuminuria Reduction Key Factor in Finerenone's Efficacy

4-month UACR reduction mediated 84% of kidney treatment effect

A micrograph and computer rendering of chronic kidney disease.

Methotrexate Tied to Greater Risks for Older Patients With CKD

FDA should consider warning labels based on study results, researchers argue

FDA ADCOMM taurolidine + heparin catheter lock solution (Defencath) over a photo of a man receiving dialysis.

FDA OKs Product to Thwart Bloodstream Infections During Dialysis

Taurolidine-heparin solution reduced infections by 71% versus heparin alone

Kidney Week over a photo of Pennsylvania Convention Center in Philadelphia, PA.

Kidney Week Roundup: Cell Therapy Cuts Immunosuppressive Drug Use Post-Transplant

Plus: bardoxolone methyl for diabetic kidney disease and spironolactone in hemodialysis patients

Kidney Week over a photo of Pennsylvania Convention Center in Philadelphia, PA.

木瓜直播 Transplant Rates Stubbornly Resist Systems Intervention in Canada

Multi-pronged approach to boost living and deceased donor transplant fails in randomized trial

Sparsentan Bests Irbesartan for Preserving Kidney Function in IgA Nephropathy

Proteinuria reduction and slower eGFR decline in 2-year PROTECT trial

ERA and SGLT2 Inhibitor Combo Cuts Albuminuria in Chronic Kidney Disease

But ZENITH-CKD trial had to pivot to only using low-dose zibotentan due to fluid retention

Kidney Week over a photo of Pennsylvania Convention Center in Philadelphia, PA.

Sparsentan Failed to Preserve Kidney Function Over Time in FSGS

However, more patients on the drug achieved partial remission of proteinuria vs irbesartan

Kidney Week over a photo of Pennsylvania Convention Center in Philadelphia, PA.

Mid-Stage Win for Novel IgA Nephropathy Drug

APRIL-neutralizing antibody sibeprenlimab reduced proteinuria and stabilized eGFR

A photo of a man receiving dialysis in the intensive care unit.

How to Deprescribe Dialysis After Patients Leave the Hospital

Acute kidney injury patients should not be left on dialysis longer than necessary

FDA APPROVED tenapanor (Xphozah) over a computer rendering of chronic kidney disease.

FDA Approves First Phosphate Absorption Inhibitor for CKD

Tenapanor indicated for adults on dialysis who fail on phosphate binders

FDA APPROVED empagliflozin (Jardiance) over a computer rendering of and micrograph of chronic kidney disease

FDA Approves Another SGLT2 Inhibitor for Treating CKD

Empagliflozin adds indication in adults, regardless of diabetes status

A photo of surgeons performing this pig-to-human kidney transplant.

Pig-Kidney Xenotransplants Prove Successful in Two Brain-Dead Men

"Life-sustaining kidney function" was seen with gene-edited pig kidneys

A photo of patients at a dialysis clinic.

Hemodiafiltration Reduced Dialysis Mortality in Kidney Failure

Randomized trial strengthens the argument for adopting this type of dialysis beyond the ICU

SCAI over a photo of the Phoenix Convention Center.

TAVR Valves Fail Fast in ESRD, Study Shows

Group predisposed to calcification shows double digit rate within 6 months

A photo of a young man looking at a laptop while receiving dialysis

Experts Outline Strategies for Boosting Equity in Chronic Kidney Disease

Race-neutral calculations for kidney function, leveling the playing field on waiting lists

AACE over a photo of the San Diego Convention Center in San Diego, CA.

GLP-1 RAs Safe Months After 木瓜直播 Transplant

Helped diabetics cut down on daily insulin dose, body weight

AACE over a photo of the San Diego Convention Center in San Diego, CA.

Vascular Complications Big Contributor to Diabetes Deaths

Diabetic nephropathy was most common of the fatal complications, study showed

A close up photo of calciphylaxis.

Sodium Thiosulphate Not Much Help for Calciphylaxis in CKD

Though used off-label for years, treatment isn't very beneficial

NKF over a photo of the Austin Convention Center in Austin, Texas.

NKF Roundup: Latest Data on Tolvaptan, Terlipressin, and Lumasiran

More research from the National Kidney Foundation Spring Clinical Meeting

NKF over a photo of the Austin Convention Center in Austin, Texas.

Another Measure of Terlipressin Success in Hepatorenal Syndrome

Goal of 30% reduction in serum creatinine in the absence of full response or HRS reversal

NKF over a photo of the Austin Convention Center in Austin, Texas.

Long COVID Patients on Dialysis See Elevated Oxidative Stress Markers

Temporary vascular access, uncontrolled hypertension may be risk factors in this population

A computer rendererd diseased kidney cutaway over a brain with a stroke highlighted.

Stroke Outcomes Provide Some Clarity on Kidney-Brain Connection

Kidney dysfunction, kidney damage increase risks in different ways, say researchers

A photo of a senior man helping his adult autistic son into the family minivan.

木瓜直播 Transplant Less Likely in Adults With Developmental Disabilities

"Urgent need" for anti-discrimination initiatives to promote equitable care, researchers argue

A photo of a donor kidney being preserved by a cold perfusion machine.

Chilling Donors Not as Good as Machine Perfusion for 木瓜直播 Transplant

Noninvasive cooling before organ removal didn't measure up for early organ function

Close-up image of a senior woman taking out pills from a pill bottle.

Combo Treatment Could Delay Kidney Failure for Years in Nondiabetic CKD

Big benefits projected with SGLT2/RAAS inhibitor combination therapy

A kidney patient receives treatment at a hospital.

Watch for Severe Hypocalcemia in Dialysis Patients on Prolia, FDA Warns

Agency said potential risk may require more frequent blood calcium monitoring

ASN over a computer rendering of kidneys highlighted in white.

Saline Goes Head-to-Head With Balanced Crystalloid IV Fluids for 木瓜直播 Transplant

Researcher argued saline should be reconsidered as the standard IV fluid used

ASN over a computer rendering of kidneys highlighted in white.

Not So Cool After All: No CV Benefit With Lower-Temp Dialysate in Hemodialysis

Some patients in MyTEMP trial even complained cooler dialysate was "worst possible feeling"

ASN over a computer rendering of kidneys highlighted in white.

Empagliflozin Protects At-Risk Patients From CKD Progression

Also cut risk for cardiovascular-related death and worsening kidney function

ASN over a computer rendering of kidneys highlighted in white.

Stop RAS Inhibitors in Advanced CKD? STOP ACEi Trial Sheds Some Light

Findings do not support discontinuation to improve kidney function, researchers say

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