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Diabetes

News, opinions and meeting coverage in nephrology.

Early Weight Loss With Saxenda Predicts More

Conversely, initial nonresponse is typically maintained

Weight-Loss Surgery a Safe Option for Mildly Obese With T2D

Patients faced a 4.2% complication rate in 30 days

T1D Patients Face Nearly Double Risk for Dementia

Findings still significant after controlling for vascular risk factors.

GI Events Do Not Explain Weight Loss With Saxenda

No difference in weight loss between patients who had nausea and vomiting with diet drug, and those who didn't.

Three Diabetes Drugs Linked to Ketoacidosis, FDA Warns

FDA targets SGLT2 inhibitors canagliflozin, dapagliflozin, and empagliflozin.

Enzyme Rise May Link GLP-1, Pancreatitis

Levels of lipase and amylase don't increase after meals in patients not taking GLP-1 drugs.

TECOS Top Line: No Increase in CV Risk with DPP-4 Inhibitor

Primary and secondary endpoints met for those on sitagliptin.

Slippery Slope: Diet Drugs No Help for Heart

In another edition of the Slippery Slope series examining use of surrogate endpoints in drug approvals, 木瓜直播 and the Milwaukee Journal Sentinel find diet drugs are approved without solid evidence of benefits, but with hints of harm.

Prediabetes Patients Have Fewer Gut Bugs

A change for the worse apparent in the intestinal microbiome.

Endo Apps: How to Get Useful Glucose Meter Data

There are several options for downloading and interpreting important data from diabetes patients.

Morning Break: Penis Reduction? Patient Suffering

Health news and commentary from around the Web, gathered by the 木瓜直播 staff.

Diabetes: Is This Tattoo Worth a 1,000 Needle Pricks?

UCSD researchers report early results on a tattoo to measure blood sugar.

Onglyza OK in Renal Patients

No increase in cardiovascular events seen in renally impaired SAVOR patients.

Gut Hormone May Up Dehydration Risk in T2D

Endogenous glucagon-like peptide-1 appears to inhibit fluid intake.

New Treatments for High Potassium on the Horizon

But ultimate success is far from guaranteed.

Stent Graft Keeps Vascular Access Clear

Should change practice, study leader says.

Insulin and Insulina: Bridging the Gap

Physicians need to be aware of patients' beliefs about medicinal plants.

Aphrodisiac Aids Genetic Type 2 Diabetes

About 4% of diabetes patients may benefit from yohimbine.

Review: Telcare Glucose Meter

An easy-to-use glucose monitor uploads data to the cloud for ready access.

Metformin and TSH: Is There a Link?

Canadian study suggests raises questions about metformin use in diabetics with underlying hypothyroidism.

HypoMap: A New Way to Track Hypoglycemia

Keeping accurate tabs on hypoglycemic events is a challenge, since they often happen between clinic visits. But Joslin Diabetes Center and technology company Glooko are trying to change that.

Glucometer Control Test Underused in Diabetes

ORLANDO -- Control solution for ensuring the proper function of glucose meters didn't appear to be a priority among physicians, pharmacists, or patients, researchers reported here.

Patients Want Diabetes-Friendly Meals on the Menu

ORLANDO -- It's easy to find heart-healthy or vegetarian-friendly meals labeled on restaurant menus, but diabetes patients are often left in the dark about options best suited to them.

FDA: No Clear Sign of Harm With Olmesartan in Diabetics

The evidence linking use of the angiotensin II receptor blocker (ARB) olmesartan in patients with diabetes and increased cardiovascular risk is not conclusive, according to a completed FDA safety review.

Victoza Accused of Causing Pancreatitis

The watchdog group Public Citizen has conducted its own analysis of FDA adverse event reports and concluded that the type 2 diabetes drug liraglutide(Victoza) likely causes pancreatitis, the group said.

Small eGFR Drops May Predict Kidney Outcomes

Declines in estimated glomerular filtration rate (eGFR) smaller than those that currently attract clinical attention may help predict the risk of end-stage renal disease, researchers reported.

The Day My Brother Became a Statistic

My brother would have turned 37 today. Instead, he became a statistic in 1995.

Hypoglycemia at Night Tied to Arrhythmias

Nocturnal hypoglycemia was a major risk factor for cardiac arrhythmias in type 2 diabetes patients who were already at an increased risk for cardiovascular events, according to British researchers.

Fatty Liver Tied to Diabetes, Atherosclerosis

LONDON -- Non-alcoholic fatty liver disease (NAFLD) is an independent predictor of both type 2 diabetes and carotid atherosclerosis, according to two studies presented here at the annual meeting of the European Association for the Study of the Liver.

ACC: Metformin No Help in MI Recovery

WASHINGTON -- Metformin started soon after reperfusion in the acute setting didn't help cardiac function recover in nondiabetic heart attack patients, a trial showed.

New Guideline Lowers eGFR for Dialysis Start

New Canadian guidelines suggest that nephrologists can wait to start dialysis in some chronic kidney disease patients until their estimated glomerular filtration rate drops below the 10 to 12 mL/min now commonly used.

11 Endocrinology Apps for Docs' Toolboxes

Even if endocrinologists aren't already suggesting smartphone apps to their patients, they've likely been asked to offer up recommendations. Here's a list of 11 apps you should know about.

Diabetes: TAVI Trumps Heart Surgery

Patients with diabetes who had aortic stenosis fared better in terms of mortality and kidney function during the first year if they underwent transcatheter aortic valve implantation (TAVI) rather than surgery, a post-hoc analysis found.

Combo Angiotensin Tx Ups Kidney Risks

ATLANTA -- In yet another trial, dual blockade of the renin-angiotensin system (RAAS) didn't slow progression of kidney disease in diabetic patients and carried a higher risk of serious adverse events compared with monotherapy, researchers reported here.

Daytime Snoozing May Tell Risk of Hypoglycemia

Older patients with diabetes who are overly tired during the day may be at a higher risk for hypoglycemia, researchers reported.

In Some Patients Metformin Impairs Thinking

The widely acclaimed diabetes drug metformin was linked with impaired brain function in patients who took the drug, although supplementation with vitamin B12 may alleviate metformin-induced deficiencies, according to new research.

Society Seconds Call for Incretin Data

SAN FRANCISCO -- The Endocrine Society has joined its voice to the recent call for incretin drugmakers to release all patient-level data on their products, the group announced at its annual meeting.

Diabetes Experts Divided About 'Lone Wolf' Butler

Top experts in diabetes and endocrinology have offered mixed reactions to a profile of Peter Butler, MD, chair of endocrinology at the University of California Los Angeles, in the New York Times.

High-Salt Diet May Boost Cortisol

Eating a diet high in sodium increased levels of cortisol and other metabolites, potentially giving rise to metabolic syndrome, researchers found.

Finger Stick Has Promise as Prediabetes Test

PHOENIX -- Measuring capillary blood via finger stick assay was as accurate as venous blood sample assays in predicting 5-year likelihood of diabetes, researchers reported here.

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