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Another CAR-T Warning; 'Sweet' Cancer Test; 'Molecular Jackhammer' Blows Up Cancer

— News, features, and commentary about cancer-related issues

MedpageToday
Onco Break over a computer rendering of a cancer cell.

Amid an ongoing investigation of CAR T-cell therapy safety, the FDA has added risk of to the boxed warning for ciltacabtagene autoleucel (Carvykti). (Fierce Pharma)

Cellular and gene therapy will likely have the biggest in the coming year. (GlobalData)

Bipartisan legislation introduced in the House aims to close a Nuclear Regulatory Commission loophole to improve patient safety of in oncology and cardiology. (Patients for Safer Nuclear Medicine)

A that measures circulating tumor DNA showed promise as a potential test to identify patients whose lung cancer is likely to respond to immunotherapy. (Johns Hopkins Medicine)

A saliva test to evaluate could help identify cancer cells in early stages of evolution. (University of Gothenburg, Cell Reports Methods)

The combination of dostarlimab (Jemperli) and niraparib (Zejula) significantly improved progression-free survival in a randomized trial of , according to a statement from GSK.

A cancer researcher's own diagnosis of provided the impetus for groundbreaking studies of new strategies to improve treatment. (University of Utah Huntsman Cancer Institute)

Fewer than half of patients with an aggressive form of received palliative care. (Urology Practice)

Mailing a letter and a signed order for ultrasound significantly increased the rate of in high-risk patients. (Hepatology Communications)

The FDA to sotorasib (Lumakras) for KRAS-mutated non-small cell lung cancer and requested a new confirmatory clinical trial, according to a statement from Amgen.

Meanwhile, that the agency approved an on-body injector for its pegfilgrastim biosimilar (Udenyca) to reduce the risk of infection, as manifested by febrile neutropenia, following chemotherapy.

The coming year could prove to be pivotal for determining the impact of Medicare and the legal challenges by drug companies. (CNBC)

In laboratory studies, a wiped out 99% of melanoma cells growing in dish. (Rice University)

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    Charles Bankhead is senior editor for oncology and also covers urology, dermatology, and ophthalmology. He joined ľֱ in 2007.