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General Gastroenterology

News, opinions and meeting coverage in gastroenterology.

A photo of the vials and packaging of Irinotecan hydrochloride.

Nanoliposomal Irinotecan Fails to Boost Survival in Treated Advanced Biliary Cancer

No difference in PFS, median OS favored control group

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Oprah Hospitalized; Senator in Car Crash; Oldest American Man Dies

Health news and commentary gathered by 木瓜直播 staff

EASL over a photo of Milano Convention Centre in Milan, Italy

Testosterone Prodrug Improves Muscle Mass, Encephalopathy in Men With Cirrhosis

Androgen precursor may help cirrhosis-related sarcopenia

EASL over a photo of Milano Convention Centre in Milan, Italy

Rifaximin Prophylaxis Fails for Bacterial Peritonitis in Cirrhotic Patients

"Is it time to say primary prophylaxis is dead?" one expert asks

EASL over a photo of Milano Convention Centre in Milan, Italy

Weight Loss/Diabetes Drug Has Positive Treatment Effect on MASH

GLP-1/GIP agonist also improved fibrosis biomarkers, liver fat, and stiffness in phase II trial

Artery Inflammation and CV Events; Stepped Palliative Care for Lung Cancer Patients

Also in TTHealthWatch: diets and medicine in IBS and active surveillance in prostate cancer

EASL over a photo of Milano Convention Centre in Milan, Italy

Novel Glucagon/GLP-1 Receptor Dual Agonist Improved MASH in Phase II Study

Effects may be related to weight loss, not changes in fibrogenesis, expert suggests

EASL over a photo of Milano Convention Centre in Milan, Italy.

Novel Intelligent Liver Function Test Platform Improves Liver Disease Diagnosis

iLFT is now an essential, highly utilized tool at one U.K. primary care system

ASCO over a photo of McCormick Place in Chicago, IL

Perioperative Chemo Extends Survival in Resectable Esophageal Cancer

Improvement also observed in complete remission rates with FLOT over CROSS regimen

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Springsteen's Health; Minimum Staffing Rule Challenged; Probiotic Sodas Probed

Health news and commentary gathered by 木瓜直播 staff

DDW over a photo of the Walter E. Washington Convention Center in Washington, DC

Increase in CRC Cases in Younger Age Groups Extends to Preteens

While cases remain rare in younger people, they're much more common than 25 years ago

DDW over a photo of the Walter E. Washington Convention Center in Washington, DC

Gallbladder Cancer Rates Stable or Down, Except in Black Patients

Black patients "presenting more often, and they're presenting at a later stage," researcher says

A computer rendering of a colorectal tumor.

Blood in Stool, Abdominal Pain Top Red Flags for Early-Onset Colorectal Cancer

These symptoms are "frequently ignored by providers as trivial," according to one expert

DDW over a photo of the Walter E. Washington Convention Center in Washington, DC

GLP-2 Analog Reduces Need for Parenteral Support in Patients With Rare GI Condition

Better outcomes in short bowel syndrome and intestinal failure with apraglutide vs placebo

FDA ADCOMM Blood-based colorectal cancer test (Shield) over a photo of the product.

Blood Test for Colon Cancer Screening May Miss Some Precancers, FDA Staff Says

Shield could boost screening compliance, but has low sensitivity for advanced adenomas

DDW over a photo of the Walter E. Washington Convention Center in Washington, DC

Endoscopic Ablation Reduces 'Hunger Hormone,' Yields Weight Loss in Early Trial

First-in-human study targets ghrelin production with mucosal ablation as obesity treatment

DDW over a photo of the Walter E. Washington Convention Center in Washington, DC

Healthcare Use Reduced When Female Gastroenterologists See Patients

Female patients appeared to derive the greatest benefit, researchers say

DDW over a photo of the Walter E. Washington Convention Center in Washington, DC

Can Robots Make Gallbladder Surgery Safer?

Observational study suggests benefit compared with laparoscopic surgery

NKF over a photo of Long Beach Convention and Entertainment Center, in Long Beach, CA

Gastrointestinal Bleeding More Common in Advanced CKD

Risk was significantly higher regardless of dialysis status

A computer rendering of a rotavirus particle.

For Most, Rotavirus Is Now Just Another Cause of Gastroenteritis

Some patients may need testing, IV rehydration, experts say

A photo of a female physician holding a colonoscope.

Colonoscopy Near Time of Joint Replacement Doesn't Increase Infection Risk

However, several comorbidities, male sex may play a role

A photo of a pregnant woman holding a blisterpack of tablets.

Rare Pregnancy Problem Linked to Thiopurines, FDA Says

Agency finds risk for intrahepatic cholestasis of pregnancy mostly in IBD, lupus patients

Close-up shot of pediatrician giving baby intramuscular injection in arm.

Antibiotics in Infancy Tied to Higher Risk for Atopic Dermatitis

An increased number of antibiotic courses corresponded to a dose-response-like increased risk

A photo of bagged breast milk in a refrigerator.

Breast Milk Enema Helps Preterm Infants Pass Meconium

Infants also moved to enteral feeding faster, randomized Chinese trial showed

A photo of a female physician administering oral rotavirus vaccine to a baby in his mothers arms.

Rotavirus: Then and Now

Many pediatric hospital residents "have never seen a case of rotavirus," said Paul Offit, MD

A transmission electron micrograph of rotaviruses

Rotavirus Still Ranks High as Cause of Acute Gastroenteritis in Children

Recent research sheds light on how the virus can cause such severe symptoms

FDA RECALL Obsidio Conformable Embolic over a computer rendering of the product.

FDA Slaps Embolization Device With Class I Recall After Deaths

Increased bowel ischemia risk when Obsidio Embolic is used for lower GI bleeds

A computer rendering of an inflamed appendix.

Oral Antibiotics Alone Miss the Mark for Uncomplicated Acute Appendicitis

But adverse events, quality of life, and patient satisfaction similar to oral/IV approach

AACR over a photo of San Diego Convention Center in San Diego, CA

Bispecific Checkpoint Inhibitor Improves Survival in Advanced Gastric/GEJ Cancer

Almost 50% improvement in median survival, but against a suboptimal control regimen

A photo of a mature woman looking at her phone while receiving chemotherapy.

Chemotherapy/ICI Combos Falter as Second-Line Treatment for Gastric Cancer

FOLFIRI plus durvalumab, with or without tremelimumab, no help after first-line chemotherapy

A photo of a man meeting with a male physician via his laptop.

Telehealth Improves Hepatitis C Treatment in Patients With Opioid Use Disorder

Facilitated telemedicine embedded into opioid treatment programs boosted HCV cure rates

A photo of a gastroenterologist holding an endoscope.

GLP-1 Users May Have Increased Endoscopy-Related Aspiration Pneumonia Risk

Overall incidence is still low, however

A photo of Kate Middleton, The Princess of Wales

Kate Middleton's Cancer: What to Know About 'Preventative' Chemotherapy

And what abdominal surgery could mean in the context of cancer

A photo of a woman holding a surgical drainage container post-surgery.

Reconsider Insertion of Abdominal Drains After Distal Pancreatectomy, Study Suggests

Rate of major morbidity was non-inferior in the no-drain group compared with the drain group

A computer rendering of a hemorrhage

Concomitant SSRI and Oral Anticoagulant Use Tied to Major Bleeding Risk

Patients taking both drugs should be closely monitored, researchers advised

A scanning electron microscope image of fecal microbiota

FDA Tries to Close the Lid on Poop Transplant Company

Fecal microbiota transplant business needs a BLA or IND to operate, agency says

FDA APPROVED tislelizumab (Tevimbra) over a computer rendering of esophageal cancer.

New PD-1 Inhibitor Approved for Esophageal Cancer

Tislelizumab improved median OS from 6.3 months with chemotherapy to 8.6 months

FDA APPROVED resmetirom (Rezdiffra) over a computer rendering of a transparent body with the liver highlighted.

FDA Approves First-Ever Drug for Serious Liver Condition

Resmetirom indicated for NASH patients with liver scarring

A computer rendering of hepatitis C viruses

Treating Kids' HCV Early May Boost Lifetime Health Outcomes and Save Money

Modeling study suggests benefits for treating at age 3 instead of age 6

A computer rendering of Helicobacter pylori bacterium.

More Evidence Linking H. Pylori Infection to Colorectal Cancer

Increased CRC incidence and mortality, significantly reduced by infection treatment

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