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75% of Adults Overweight or Obese; Global Diabetes Tx Lacking; Hidden Bone Data?

— News and commentary from the endocrinology world

MedpageToday
Endo Break over a computer rendering of a man with illustrated body organs.

Three-fourths of U.S. adults are now overweight or have obesity, with nearly 260 million by 2050. (The Lancet)

According to another study in The Lancet, almost 60% of the across the globe didn't receive treatment.

A Swedish cohort study of kids with type 1 diabetes showed that poor glycemic control . (Journal of Clinical Endocrinology & Metabolism)

Novo Nordisk will and instead shift focus to making its GLP-1 injectables, the drugmaker said. (Reuters)

In the 12-patient phase III VENTURE trial, the melanocortin-4 receptor agonist setmelanotide (Imcivree) by 52 weeks among children ages 2 to 5 years with rare genetic obesity. Maker Rhythm Pharmaceuticals sent the data to the FDA looking to expand the drug's label to this younger group of kids. (Lancet Diabetes & Endocrinology)

For older adults on long-term statin therapy, SGLT2 inhibitors were associated with a compared with DPP-4 inhibitors in a case-control study. (JAMA Network Open)

Telehealth company Hims & Hers Health launched , in which patients can share details about their challenges finding weight loss and diabetes drugs.

Experts warned about the "chilling" effect of the over gender-affirming care. (Salon)

Though published 9 months ago, a newly discovered hidden tab in an Excel spreadsheet of phase I data on Amgen's investigational obesity drug maridebart cafraglutide revealed that patients on the highest dose across 12 weeks of treatment. However, that the study findings "do not suggest any bone safety concern." (FierceBiotech)

In a JAMA viewpoint on the , researchers said that "quantifying whether short-term therapy results in some enduring benefit, a return to pretreatment cardiovascular risk, or rebound risk in excess of baseline risk should be a priority."

A federal appeals court ruled that an Indiana law should remain in effect. (The Hill)

People diagnosed with type 2 diabetes at a younger age may have compared with those diagnosed later in life, especially for those with obesity. (PLOS One)

  • author['full_name']

    Kristen Monaco is a senior staff writer, focusing on endocrinology, psychiatry, and nephrology news. Based out of the New York City office, she’s worked at the company since 2015.