Meeting Coverage
SABCS
San Antonio Breast Cancer Symposium
Latest SABCS Meeting Coverage
Two-thirds of patients progression free at 6 months with zanidatamab, palbociclib, fulvestrant
No difference for survival outcomes for annual versus around every 2 years
However, the surgery did reduce risk of contralateral breast cancer
Local recurrence rate of 1% at 5 years in women ages 50-69 with genomically low-risk disease
Datopotamab deruxtecan was safe and boosted quality of life
But better safety profile versus continued pembrolizumab plus chemotherapy
Younger age, embryo/oocyte cryopreservation at diagnosis tied to an increased chance of pregnancy
Promising early results with pembrolizumab, nivolumab but event-free survival data still pending
Neoadjuvant administration of immunotherapy remains the preferred approach
Study showed no increase in disease progression when omitting regional nodal irradiation
Adding agent to T-DM1 resulted in 2-month progression-free survival improvement
Enthusiasm tempered by immune-related adverse events, diabetes with PD-1/LAG-3 combination
First comparison of targeted sentinel node assessment shows no difference in recurrence rates
In phase III trial, capivasertib benefited patients with or without AKT pathway alterations
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ASTRO: American Society for Radiation Oncology
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ESMO: European Society for Medical Oncology
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ASCO: American Society of Clinical Oncology
May 2024